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Evans syndrome, a combination of autoimmune hemolytic anemia and idiopathic thrombocytopenic
purpura, relapses freguently and is refractory to conventional treatment such as corticosteroid,
immunosuppressive agents, splenectomy and plasma exchange. Recently Oda et al applied high dose
immunoglobulin (400/kg/day for 4 days repeated 2 weeks later) to 5 month-old infant with refractory
Evans syndrome, and was successful in maintaining remission for five years and nine... |